What is considered a "low" IGF1 level?

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What is considered a "low" IGF1 level?

This topic contains 6 replies, has 2 voices, and was last updated by  Tobias Karlsson 10 years, 7 months ago.

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  • Hello,

    first time on this forum and finding my way around! It is very inspiring to see what other people experience and the knowledge they can share.

    I am on 5:2 for soon a year, male, 35 years old, around 70kg and 182 cm. I had my first IGF1 test made in April and it was 121.3 ng/mL. My understanding is that it is low, but not in any way extremely low. Glucose was on 4.1, which is also healthily low. My cholesterol was: triglycerid 0.87, HDL 1.50, LDL 3.0 – so all good!

    What I am trying to understand is if there is any threshold for IGF1, under which the cell repair mode starts (does it have to be extremely low to have any effect at all)? Or is the risk for cell damage linear, so that e.g. a level of 150ng/mL means a better protection or reduced risk than 170, and 130 means a better protection or reduced risk than 150?

    My gut feeling is that it is a healthy level and should at least mean that I am not in a higher risk category. Thanks for any advice on the subject.

    hi Tobias Karlsson,

    just got my results & mine were normal

    here is what normal was on my paper

    mine was 6 normal is 5-34

    unfortunatly my triglyserides were not 268 πŸ™

    also click on michael’s replies or topics or his dr wife clare 2 c if they discussed it

    http://thefastdiet.co.uk/forums/users/michael/replies/

    http://thefastdiet.co.uk/forums/users/mimi/replies/

    http://thefastdiet.co.uk/forums/users/clare/replies/

    hope this helps

    Thanks wiltldnrUSA!

    I will try my luck there πŸ™‚

    Wow, an IGF1 level of 6 seems extremely low… I think the conversion factor is something like 7.5 between the different measurement systems used. So an IGF1 levelof 121.3, that I have, corresponds to around 16 in the units that Michael mentions in his conversation with Mr Luongo in “Eat fast and live longer”. I remember that he had a value = 28 which was “not very bad, but puts him in a higher risk category”. So I am trying to figure out how my level of 16 compares to that and what implications it has… I saw some other people having values around 103-106 on this diet where around 75 is the minimum of the range that is considered normal in human beings. Now, that would (if I am right) correspond to a value of around 10 so if you are on 6… that is really low. Or are we talking about different units here?

    normal is 5-34 it was on the lab test results went back w/ ruler 2 c if i read it wrong. nope IGF binding protein 1. (IGFBP-1)

    it must b different units. doc was happy that it was normal

    found an article mayo clinic

    4 20 & up age

    20 years
    98-443

    21-25 years
    83-344

    26-30 years
    75-275

    31-35 years
    71-241

    36-40 years
    69-226

    41-45 years
    64-210

    46-50 years
    59-201

    51-55 years
    56-201

    56-60 years
    51-194

    61-65 years
    47-191

    66-70 years
    46-195

    71-75 years
    42-187

    76-80 years
    39-184

    80-85 years
    37-182

    85-90 years
    35-182

    Females:
    Age
    ng/mL
    0.1 Percentile (ng/mL)

    20 years
    97-398

    21-25 years
    84-323

    26-30 years
    77-271

    31-35 years
    73-244

    36-40 years
    68-225

    41-45 years
    62-205

    46-50 years
    56-194

    51-55 years
    53-191

    56-60 years
    45-173

    61-65 years
    41-168

    66-70 years
    39-168

    71-75 years
    36-166

    76-80 years
    35-168

    80-85 years
    35-179

    85-90 years
    33-179

    Reference values have not been established for patients that are >90 years of age.

    IGF-1 reference values according to Tanner stages I-V(2)
    Males
    Stage I: 83-255 ng/mL
    Stage II: 114-440 ng/mL
    Stage III: 236-516 ng/mL
    Stage IV: 218-580 ng/mL
    Stage V: 229-522 ng/mL
    Females
    Stage I: 90-324 ng/mL
    Stage II: 104-456 ng/mL
    Stage III: 249-519 ng/mL
    Stage IV: 238-574 ng/mL
    Stage V: 187-509 ng/mL

    Note: Puberty onset, ie the transition from Tanner stage 1 (prepubertal) to Tanner stage 2 (early pubertal), occurs for girls at a median age of 10.5 (+/-2) years and for boys at a median age of 11.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls. By contrast, for boys there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage 5 (young adult) should be reached by age 18.

    INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3

    20 years: 2.9-7.2 mcg/mL
    21-25 years: 3.4-7.8 mcg/mL
    26-30 years: 3.5-7.6 mcg/mL
    31-35 years: 3.5-7.0 mcg/mL
    36-40 years: 3.4-6.7 mcg/mL
    41-45 years: 3.3-6.6 mcg/mL
    46-50 years: 3.3-6.7 mcg/mL
    51-55 years: 3.4-6.8 mcg/mL
    56-60 years: 3.4-6.9 mcg/mL
    61-65 years: 3.2-6.6 mcg/mL
    66-70 years: 3.0-6.2 mcg/mL
    71-75 years: 2.8-5.7 mcg/mL
    76-80 years: 2.5-5.1 mcg/mL
    81-85 years: 2.2-4.5 mcg/mL

    Tanner Stages:
    Males
    Stage I: 1.2-6.4 mcg/mL
    Stage II: 2.8-6.9 mcg/mL
    Stage III: 3.9-9.4 mcg/mL
    Stage IV: 3.3-8.1 mcg/mL
    Stage V: 2.7-9.1 mcg/mL
    Females
    Stage I: 1.4-5.2 mcg/mL
    Stage II: 2.3-6.3 mcg/mL
    Stage III: 3.1-8.9 mcg/mL
    Stage IV: 3.7-8.7 mcg/mL
    Stage V: 2.6-8.6 mcg/mL

    http://www.mayomedicallaboratories.com/interpretive-guide/?alpha=I&unit_code=35100

    did u find any in michael’s replies or clare’s?

    it is still not up on forum so will repeat these links

    also click on michael’s replies or topics or his dr wife clare 2 c if they discussed it

    http://thefastdiet.co.uk/forums/users/michael/replies/

    http://thefastdiet.co.uk/forums/users/mimi/replies/

    http://thefastdiet.co.uk/forums/users/clare/replies/

    success

    Hi,

    thanks – I was looking for answers there but could not find it. To be honest I did not manage to raise a new topic there, but I could only look at this on and off during the day so I will try again. Appreciate the help.

    ur IGF1 level of 121.3,

    should b normal based on the chart

    31-35 years
    73-244
    36-40 years
    68-225

    congrats πŸ™‚

    Haha, thanks! I will just stop worrying about this level and try to keep it there or below πŸ™‚ – I think I will live “happy ever after” if I manage πŸ™‚

    You have been most helpful, wiltldnrUSA! Appreciated!

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